There are twenty-four high quality studies (Adachi 2004, Adrayanti 2017, Aga 2018, Aglietti 2010, Beyaz 2017, Ibrahim 2009, Jarvela 2017, Jarvela 2008, Kang 2015, Karikis 2016, Liu 2016, Mayr 2016, Mayr 2018, Mohtadi 2019, Mohtadi 2015, Mohtadi 2016, Núñez 2012, Sasaki 2016, Sun 2015, Suomalainen 2012, Suomalainen 2011, Yang 2017, Zhang 2014, Irrgang 2021) that compare single to double bundle ACL reconstruction. The majority of the studies demonstrate no statistically significant difference in any outcome parameters. Five meta-analyses demonstrated no statistically significant difference between single and double bundle reconstruction in post-operative pain, Lysholm, or IKDC subjective knee scores.
Benefits/Harms of Implementation
As with all surgery procedures, there are surgical risks and complications including but not limited to, graft failure, arthrofibrosis, infection, neurovascular injury, and anesthetic complications.
Outcome Importance
The many high quality studies demonstrate that either single- or double-bundle ACL reconstruction can result in excellent functional and clinical outcomes.
Cost Effectiveness/Resource Utilization
While equivalent in outcomes, double-bundle ACL reconstructions involve increased surgical time and increased costs.
Acceptability
Single and double bundle ACL reconstructions are both acceptable procedures for the reconstruction of ACL deficient knees, when indicated.
Feasibility
Both single- and double-bundle ACL reconstruction are feasible surgical treatment for ACL reconstruction.
Future Research
While no differences have been noted at 10-year follow up, future research is indicated to determine any differences between single and double bundle ACL reconstructions in the rate of degenerative changes at long-term (> 20 year) follow up.
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- Zhang, Z., Gu, B., Zhu, W., Zhu, L. Double-bundle versus single-bundle anterior cruciate ligament reconstructions: a prospective, randomized study with 2-year follow-up. European journal of orthopaedic surgery & traumatologie 2014; 4: 559-65
- Yang, J., Fu, S., Song, Y. A prospective randomized controlled trial to evaluate clinico-radiological outcome of arthroscopic single bundle versus double bundle anterior cruciate ligament reconstruction. International journal of clinical and experimental medicine 2017; 1: 1087-1093
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- Mohtadi, N., Chan, D., Barber, R., Paolucci, E. O. Reruptures, Reinjuries, and Revisions at a Minimum 2-Year Follow-up: A Randomized Clinical Trial Comparing 3 Graft Types for ACL Reconstruction. Clinical Journal of Sport Medicine 2016; 2: 96-107
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- Liu, X., Zhang, H., Feng, H., Hong, L., Wang, X. S., Song, G. Y. Is It Necessary to Repair Stable Ramp Lesions of the Medial Meniscus During Anterior Cruciate Ligament Reconstruction? A Prospective Randomized Controlled Trial. American Journal of Sports Medicine 2017; 5: 1004-1011
- Karikis, I., Desai, N., Sernert, N., Rostgard-Christensen, L., Kartus, J. Comparison of Anatomic Double- and Single-Bundle Techniques for Anterior Cruciate Ligament Reconstruction Using Hamstring Tendon Autografts: A Prospective Randomized Study With 5-Year Clinical and Radiographic Follow-up. American Journal of Sports Medicine 2016; 5: 1225-36
- Kang, H. J., Wang, X. J., Wu, C. J., Cao, J. H., Yu, D. H., Zheng, Z. M. Single-bundle modified patellar tendon versus double-bundle tibialis anterior allograft ACL reconstruction: a prospective randomized study. Knee Surgery, Sports Traumatology, Arthroscopy 2015; 8: 2244-2249
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- Beyaz, S., Guler, U. O., Demir, S., Yuksel, S., Cinar, B. M., Ozkoc, G., Akpinar, S. Tunnel widening after single- versus double-bundle anterior cruciate ligament reconstruction: a randomized 8-year follow-up study. Archives of Orthopaedic & Trauma Surgery 2017; 11: 1547-1555
- Adravanti, P., Dini, F., de Girolamo, L., Cattani, M., Rosa, M. A. Single-Bundle versus Double-Bundle Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Controlled Trial with 6-Year Follow-up. The Journal of Knee Surgery 2017; 9: 898-904
- Aga, C., Risberg, M. A., Fagerland, M. W., Johansen, S., Troan, I., Heir, S., Engebretsen, L. No Difference in the KOOS Quality of Life Subscore Between Anatomic Double-Bundle and Anatomic Single-Bundle Anterior Cruciate Ligament Reconstruction of the Knee: A Prospective Randomized Controlled Trial With 2 Years' Follow-up. American Journal of Sports Medicine 2018; 10: 2341-2354
- Aglietti, P., Giron, F., Losco, M., Cuomo, P., Ciardullo, A., Mondanelli, N. Comparison between single-and double-bundle anterior cruciate ligament reconstruction: a prospective, randomized, single-blinded clinical trial. American Journal of Sports Medicine 2010; 1: 25-34
- Adachi, N., Ochi, M., Uchio, Y., Iwasa, J., Kuriwaka, M., Ito, Y. Reconstruction of the anterior cruciate ligament. Single- versus double-bundle multistranded hamstring tendons. Journal of Bone & Joint Surgery - British Volume 2004; 4: 515-20
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