We reviewed two high quality studies that evaluated the influence of an opioid administered intraoperatively during primary TJA on postoperative pain, opioid consumption, and complications.
Both studies evaluated postoperative opioid consumption after administering an intraoperative opioid during primary TJA. They both found that administering an intraoperative opioid reduced postoperative opioid consumption compared to placebo within the first 72 hours after surgery.
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