Decreased Risk of CTS
Moderate evidence supports that physical activity/exercise is associated with a decreased risk of developing carpal tunnel syndrome (CTS).

Rationale
Vigorous exercise was associated with reduced risk of CTS in one moderate quality study (Goodson, 2014).  In the same study, increased risk of CTS was associated with wrist straining exercise (e.g., weight lifting, mountain biking, racquet sports), but that risk was reduced if there was also vigorous exercise.  Another moderate quality study (Eleftheriou, 2012) found an association between regular physical activity (e.g., basketball, football, tennis, jogging, and swimming) and reduced risk of CTS.

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