Increased Risk of CTS (Limited Evidence)
Limited evidence supports that the following factors are associated with the increased risk of developing carpal tunnel syndrome (CTS):
• Dialysis
• Fibromyalgia
• Varicosis
• Distal radius fracture

Comorbidities including dialysis, fibromyalgia, and varicosis each had one moderate quality study (Shin, 2008; Fahmi, 2013; De Krom, 1990) showing that each has a significantly increased risk of CTS.
Wrist fracture showed an increased risk of CTS in two moderate quality studies (Geoghegan, 2004; Dyer, 2008). One moderate quality study (Morgenstern, 1991) showed an insignificant relationship, but that study included only female participants and therefore the findings may not be generalizable.