Watts et al (2004) randomized 64 patients to have a carpal tunnel release under local anesthesia using either plain lidocaine or lidocaine buffered with sodium bicarbonate. One minute after infiltration, and before application of a tourniquet, pain was measured on a 100 mm visual analog scale. Although patients who received buffered lidocaine reported less pain, the difference from those receiving the plain lidocaine was not statistically significant.
- Vossinakis,I.C.; Stavroulaki,P.; Paleochorlidis,I.; Badras,L.S. Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression. J Hand Surg Br; 2004/8: 4
- Watts,A.C.; Gaston,P.; Hooper,G. Randomized trial of buffered versus plain lidocaine for local anaesthesia in open carpal tunnel decompression. J Hand Surg Br; 2004/2: 1