Surgical Release Location
Strong evidence supports that surgical release of the transverse carpal ligament should relieve symptoms and improve function.

Rationale
There were 17 high quality (Atroshi 2006, Castillo 2014, Cellocco 2005, Cellocco 2009, Cresswell 2008, Gerritsen 2002, Hamed 2009, Hui 2005, Ismatullah 2013, Jarvik 2009, Larsen  2013, Malhotra 2007, Saw 2003, Sennwald 1995, Suppaphol 2012, Trumble 2002, and Zyluk 2006) and 10 moderate quality (Andreu 2013, Aslani 2012, Capa-Grasa 2014, Dumontier 1995, Elsharif 2014, Faraj 2012, Ly-Pen 2012, Tarallo 2014, Tian 2007, and Ucar 2012) studies demonstrating that release of the transverse carpal ligament is an effective treatment for patients with CTS.
 

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