Laser Therapy
Limited evidence supports that laser therapy might be effective compared to placebo.

Several high quality studies (Chang 2008, Evcik 2007, Fusakul 2014) evaluated the use of laser therapy in treating carpal tunnel syndrome.  In a randomized, controlled trial, Chang 2008 evaluated the efficacy of a laser (830nm diode with 10Hz, 50% duty cycle, 60 mW, 9.7J/cm) versus placebo laser on the treatment of carpal tunnel syndrome.  The treatment was rendered for 10 minutes daily for 5 days a week for two weeks.  After 4 weeks, the laser treatment provided significantly improved grip strengths, digital prehension, and lateral prehension (p<0.05).  In a randomized controlled trial, Evcik 2007 evaluated the efficacy of laser (7J/2min) versus placebo laser.  The treatment was rendered five times per week for two weeks.  After four weeks, significant improvement in grip strength and pinch strength was noted (p<0.001); there was also significant improvement in sensory nerve velocity, sensory distal latency, and motor distal latency (p<0.001).  In a randomized double-blinded controlled trial, Fusakul 2014 evaluated the efficacy of laser (gallium-aluminum-arsenide at a dose of 18J/session) versus placebo laser.  Grip strength and pinch strength was significantly improved.  At 12 weeks follow up, distal motor latency was significantly improved (p<0.05).