Ketoprofen Phonophoresis
Moderate evidence supports that ketoprofen phonophoresis could provide reduction in pain compared to placebo.

Rationale
In a randomized controlled trial, Soyupek 2012 compared phonophoresis with corticosteroid versus phonophoresis with nonsteroidal anti-inflammatory drug use.  Phonophoresis with corticosteroid showed statistically significant improved in VAS score.  In a prospective, randomized, double-blinded controlled trial, Yildiz 2011 compared the efficacy of 2 weeks of treatment with placebo ultrasound, ultrasound, or ketoprofen phonophoresis.   The group that underwent ketoprofen phonophoresis for two weeks demonstrated significant improvement in VAS score over the sham ultrasound and the ultrasound group at two weeks and eight weeks.  
 

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