Lateral Wedge Insoles
We cannot suggest that lateral wedge insoles be used for patients with symptomatic medial compartment osteoarthritis of the knee.

Rationale
This recommendation is based on five studies. Four studies, one of high-strength81 and three of moderate-strength, compared outcomes using lateral wedge insoles to neutral insoles.82-84 No significant changes in pain, self-reported physical function, or Patient Global Assessment scores were seen between the two types of insoles. A fifth low-strength study compared urethane lateral wedge insoles to rubber lateral insoles, and found a statistically significant improvement in Lequesne score for urethane insoles, but this outcome was of uncertain clinical significance.85

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