TOBACCO
Limited evidence suggests that patients with symptomatic osteoarthritis of the hip who use tobacco products may be at an increased risk for adverse events after total hip arthroplasty.

Rationale

Eleven low quality studies (Burn 2019, Sali 2020, Sadr Azodi 2006, Peters 2020, Huddleston 2012, Gonzalez 2018, Sirignano 2023, Lung 2023, Peters 2021, Benes 2023, Goh 2022) were reviewed. There is a lack of clarity in the literature regarding different forms of tobacco use. Smoking is widely considered to be more significant than other forms of tobacco use. Most of the studies have investigated the effect of smoking on surgical outcome. One low quality study (Sadr Azodi 2006) showed increased systemic complications in both current and former smokers, while another prospective study (Gonzalez 2018) showed increased PJI in current and former smokers. There is a lack of clarity in literature regarding different forms of tobacco use. Lung (2023) reported that smoking is an independent risk factor for sustaining periprosthetic fracture.

Benefits/Harms of Implementation
There could be significant potential harm due to systemic complications and increased periprosthetic joint infections in smokers after total hip arthroplasty. It will result in significant financial burden and medical comorbidities. There is no benefit of smoking in patients undergoing total hip arthroplasty however, in absence of strong data, there is a concern about denial of care impatience with the smoking.

Outcome Importance
Future research will help us understand the impact of smoking on total hip arthroplasty. Postoperative complications could have a significant impact on the patient under community.

Cost Effectiveness/Resource Utilization
Any postoperative complication after total hip arthroplasty requires intense resource utilization and leads to increased cost of care.

Acceptability
There is no barrier to the acceptability of this option. Physicians should have open discussions with patients about potential downside.

Feasibility
This option does not contradict the current standard of care.

Future Research
Future well designed studies examining the effects of different forms of tobacco on the postoperative short- and long-term outcomes after total hip arthroplasty are needed. Stratification into the amount of tobacco use and those effects on outcomes are also needed. Future healthcare costs studies are also needed to determine the financial impact of tobacco use and complications after total hip arthroplasty.