One moderate quality study (Duiven 2013) and one low quality paper (Singh 2010) demonstrated less good outcomes in patients with anxiety/depression. There only being one moderate quality paper, the recommendation made was that limited evidence supports that patients with depression and/or anxiety symptoms have less improvement in patient reported outcomes with total knee arthroplasty.
- Duivenvoorden,T., Vissers,M.M., Verhaar,J.A., Busschbach,J.J., Gosens,T., Bloem,R.M., Bierma-Zeinstra,S.M., Reijman,M. Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study. Osteoarthritis Cartilage 2013/12; 12: 1834-1840
- Singh,J.A., O'Byrne,M., Harmsen,S., Lewallen,D. Predictors of moderate-severe functional limitation after primary Total Knee Arthroplasty (TKA): 4701 TKAs at 2-years and 2935 TKAs at 5-years. Osteoarthritis Cartilage 2010/4; 4: 515-521