Pharmacotherapy Role
We are unable to recommend for or against the use of pharmacotherapy in the initial treatment of patients with glenohumeral joint osteoarthritis.

Rationale
Conservative management of pain secondary to osteoarthritis frequently includes pharmacologic treatment.  Non steroidal anti-inflammatories, acetaminophen, opioids, and over–the-counter supplements are routinely used.  Despite an exhaustive literature review, there is insufficient evidence to support or refute the use of the pharmacologic treatments for shoulder arthritis.