Radiation Therapy after Resection and Reconstruction
In the absence of reliable evidence, it is the opinion of the workgroup that radiation therapy may be considered after resection and reconstruction to reduce pain, improve functional status, and reduce the need for further intervention in patients with residual tumor, or those at increased risk of tumor recurrence in the setting of metastatic carcinoma or multiple myeloma of the femur.
Treatment of Metastatic Carcinoma and Myeloma of the Femur
Joint MSTS/ASTRO/ASCO Guideline
CONSENSUS RECOMMENDATION Rationale
No investigations directly compare the impact of radiation therapy after resection and reconstruction, limiting the statements that can be made about whether radiation therapy can improve outcomes in the setting of residual disease or when there is an increased risk of tumor recurrence. However, given that radiation therapy of the femur is generally well-tolerated and residual/recurrent tumor of the femur can remain/become symptomatic, the potential benefits may be felt to outweigh the harms in select patients.